Search results for "Inflammatory cascade"

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Serum low density lipoprotein subclasses in asthma

2013

Summary Background The levels of serum low-density lipoproteins (LDL) have been implicated in the inflammatory cascade in a murine model of asthma. Recent findings suggest that LDL may modulate the inflammatory state of the asthmatic airways in humans. Objective We explored whether LDL subclasses are associated with the occurrence and severity of asthma. Methods 24 asthmatics (M/F: 11/13) and 24 healthy individuals, with normal BMI and absence of metabolic syndrome, matched for age and gender. Serum concentrations of LDL subclasses were distributed as seven bands (LDL-1 and -2 defined as large, least pro-inflammatory LDL, and LDL-3 to −7 defined as small, most pro-inflammatory LDL), using t…

AdultMalePulmonary and Respiratory Medicinemedicine.medical_specialtyVital CapacityAsthma pathogenesiPilot ProjectsSettore MED/10 - Malattie Dell'Apparato RespiratorioFEV1Forced Expiratory VolumeInternal medicineStatistical significanceAsthma pathogenesisHumansMedicineAgedAsthmaLDL subclassesAged 80 and overDyslipidemia; Asthma pathogenesis; FEV1; LDL subclassesbusiness.industryMiddle AgedSerum concentrationHypolipoproteinemiasmedicine.diseaseAsthmaLipoproteins LDLEndocrinologyDyslipidemiaMurine modelInflammatory cascadeFemaleSerum low density lipoproteinlipids (amino acids peptides and proteins)Metabolic syndromebusinessDyslipidemiaRespiratory Medicine
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